John Wayne Casserole.’

This hearty and filling John Wayne Casserole Recipe layers taco-seasoned beef, veggies, creamy cheese topping, and a Bisquick base into one easy, comforting dinner bake.

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John Wayne Casserole is a Tex-Mex-inspired dish that has all the cozy comfort a casserole brings to the table. Casseroles always fill everyone’s bellies and are usually so simple to make. You can change things up with my Chicken Casserole or try a kid favorite Sloppy Joe Casserole.

Why You Need to Make This Hamburger Casserole

With layers of seasoned ground beef, peppers, Rotel, corn, and a cheesy sour cream topping over a fluffy Bisquick crust, this beef casserole dish is perfect for feeding a hungry family or a crowd. I love that this family dinner uses simple ingredients, is so flavorful, super filling, and is surprisingly simple to put together.

This delicious John Wayne Casserole is flavorful, filling, and full of family-friendly ingredients. Perfect for busy weeknights, potlucks, or meal prepping, this casserole delivers big taste with minimal fuss. Plus, it uses pantry staples you probably already have on hand.

Lets Gather The Ingredients

• Bisquick mix
• Ground beef- I used lean ground beef, but ground turkey or chicken works well and makes a great leaner option.
• Veggies- diced white onion, diced green peppers, can of Rotel with green chiles, and frozen corn
• Taco seasoning- you can use a packet or make some Homemade Taco Seasoning
• Sour cream: Greek yogurt can be used in a pinch.
• Mayonnaise: Use real mayonnaise.
• Cheese: I used Colby Jack but you can use whatever cheese you prefer.

How To Make John Wayne Casserole

• Step 1: Add Bisquick and water to a bowl and mix until well combined. 
• Step 2: Prep a baking dish by spraying it with nonstick cooking spray and transfer the Bisquick dough mixture to it. Spread the dough out to reach the sides of the dish.
• Step 3: Add ground beef, peppers and onion to a large skillet and cook until ground beef is browned and veggies are tender. Drain excess fat and grease from the browned ground beef, pepper, and onion mixture.
• Step 4: Add the can of Rotel, corn, and taco seasoning to the mix. Stir and cook. 

• Step 5: Transfer the taco meat mixture to the dish the.
• Step 6: In a separate bowl, mix sour cream, mayo, and some of the shredded cheese until combined. 
• Step 7: Spread this sour cream mixture over the ground beef mixture. 
• Step 8: Finish off with the remaining shredded cheese before placing the dish in the preheated oven to bake uncovered until the cheese is melted and may start to turn golden brown.

Recipe Tips

• A can of drained black beans or pinto beans adds extra texture and protein. This could help bulk out this main dish even more.
• Try Monterey Jack, cheddar, pepper Jack, or a Mexican blend instead of Colby Jack.
• For a kick of heat, choose a hot version of Rotel or add diced jalapeños.
• Spray your spatula with nonstick cooking spray to help make spreading the Bisquick dough around the dish easier.